Surfactant is often used as a liquid booster in pharmaceutical products

2022-09-02 15:13:36

Surfactants are often used in industrial industries. For the use of surfactants, most of them are used in the washing and textile industries. For all fine industrial industries, it is impossible to leave the use of surfactants. All our industries related to industry, including the pharmaceutical industry, are inseparable from the use of surfactants. There is also the paper industry, which is also a field of the fine industry. In the paper industry, surfactants are also widely used.

In the pharmaceutical industry, surfactants are often used in pharmaceuticals to increase the liquid, which can make many difficult to dissolve substances become transparent solutions and increase the concentration of solutions. Moreover, in the pharmaceutical industry, surfactants are also used in the use of bactericides and disinfectants. They can denature bacterial biofilm proteins or even lose their original functions through strong interaction with bacterial biofilm proteins. Therefore, the role of surfactants is very powerful and its application is also very wide.

The characteristics of surfactants include anionic, cationic, nonionic and amphoteric surfactants. Among them, anionic surfactants include carboxylic acid salts, sulfonic acid salts, sulfate salts and phosphate salts; Cationic surfactants include aliphatic amine salts and alkyl cyclic nitrogen-containing heterocyclic salt surfactants; Nonionic surfactants include polyoxyethylene and fatty acid polyol esters; Amphoteric surfactants can be divided into betaine, amino acid, lecithin and imidazoline derivatives according to the structure of cationic part; According to the structure of the anion part, it can be divided into carboxylate, sulfate, sulfonate and phosphate. Their major feature is that they can function as cations or anions under different conditions. These surfactants have good detergency, foaming power and emulsifying power, and are resistant to acid and alkali, hard water, as well as antistatic and bactericidal effects. Some varieties also have good special functions such as retarding dyeing and color matching.

Although there are many kinds of surfactants with different functions, their molecular structure has a common feature, that is, they are all composed of hydrophilic groups and lipophilic groups (or hydrophobic groups). Hydrophilic groups can combine with water molecules to dissolve surfactants in water. It can also be said that the water solubility of surfactants mainly depends on the number, strength and connection position of hydrophilic groups in the molecular structure, It also depends on the proportion of hydrophilic groups and lipophilic groups in the molecular structure.

For surfactant molecules, common hydrophilic groups mainly include carboxylic acid group, sulfonic acid group, sulfate group, hydroxyl group, ether group, amino group, polyoxyvinyl group, etc. Lipophilic groups can dissolve the antiactivators in oils and fats. Common lipophilic groups mainly include linear or branched aliphatic alkyl groups (such as dodecyl and octadecyl), aryl groups (such as phenyl and naphthyl), and alkyl aryl groups (such as butylene and Dodecylbenzene).