Alkyl glycosides can be used to change pharmacokinetic processes

2021-10-15 14:37:21

APG is a moisture absorbing solid, which is generally dissolved in water and difficult to dissolve in some common organic solvents, but it has good solubility and surface activity in acid solution, and its solubility and surface activity in alkali solution are more prominent than other non-ionic surfactants. When in use, it can be prepared into a stable inorganic salt active solution with a concentration of 20% ~ 30%.

Alkyl glycosides are non-toxic and have high hemolytic activity. Experiments show that they have higher adsorption and permeability to biofilm than polyoxyethylene non-ionic surfactants. They can be used to change the pharmacokinetic process and improve the percutaneous absorption of effective substances.

Alkyl polyglycoside (APG) is a non-ionic surfactant synthesized from renewable plant materials such as fatty alcohol and glucose. Compared with petrochemical raw materials, it is a natural, mild and green product with sustainable development. The application of APG is helpful to the development of tableware detergent in the direction of mild, non-toxic, non irritating, good degradability and strong decontamination.

Down jacket cleaning wipes not only need to meet the decontamination requirements of laundry detergent in the national standard, but also need to consider the use feeling of wipes and make a series of adjustments. In order to have a better experience in the use process, it is necessary to be as fresh and not sticky as other wet wipes on the market, so the viscosity of wet wipes should be appropriately reduced; Since the wet towel is wiped to remove stains without rinsing, the wet towel should meet the requirements of no bubble or low bubble as much as possible during use. In the formulation, APG with good synergism and solubilization with other active agents, AE0-9 with strong detergency and low foam yield, and amino acid surfactant SCA with low viscosity and good temperature were selected for formulation study.